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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP1
All Species:
13.64
Human Site:
Y681
Identified Species:
27.27
UniProt:
O94782
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94782
NP_001017415.1
785
88207
Y681
S
K
A
D
Y
E
L
Y
N
K
A
S
N
P
D
Chimpanzee
Pan troglodytes
XP_513450
785
88166
Y681
S
K
A
D
Y
E
L
Y
N
K
A
S
N
P
D
Rhesus Macaque
Macaca mulatta
XP_001085195
784
88189
Y680
S
K
A
D
Y
E
L
Y
N
K
A
S
N
P
D
Dog
Lupus familis
XP_865460
785
88368
Y681
S
K
A
D
Y
E
L
Y
N
K
A
S
N
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJQ2
784
87438
N680
K
A
D
Y
E
L
Y
N
K
A
S
N
P
D
K
Rat
Rattus norvegicus
Q569C3
784
87311
C680
S
K
A
D
Y
E
L
C
S
K
A
S
N
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026461
794
88314
C688
G
Q
K
S
K
S
D
C
D
L
Y
S
K
P
A
Frog
Xenopus laevis
Q52KZ6
370
42846
Q267
K
R
F
K
Y
M
D
Q
L
H
R
Y
T
K
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001128140
646
73202
K543
F
Q
C
D
R
D
S
K
R
Q
T
S
G
Q
S
Nematode Worm
Caenorhab. elegans
P34547
426
48259
R323
D
D
A
E
Y
G
D
R
M
Y
D
L
V
A
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146737
368
41784
Q265
K
R
F
K
Y
I
E
Q
L
G
R
Y
K
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAM0
365
41828
Q262
K
R
F
K
Y
M
E
Q
L
G
R
Y
K
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
94.3
N.A.
88.5
88.6
N.A.
N.A.
73.1
20.5
N.A.
N.A.
N.A.
21.7
22.5
N.A.
Protein Similarity:
100
100
98.5
96.5
N.A.
93.2
92.6
N.A.
N.A.
82.4
32.8
N.A.
N.A.
N.A.
38.8
36.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
80
N.A.
N.A.
13.3
6.6
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
93.3
N.A.
N.A.
26.6
13.3
N.A.
N.A.
N.A.
33.3
20
N.A.
Percent
Protein Identity:
N.A.
21.4
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
31.5
N.A.
30.4
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
50
0
0
0
0
0
0
9
42
0
0
9
9
% A
% Cys:
0
0
9
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
50
0
9
25
0
9
0
9
0
0
9
34
% D
% Glu:
0
0
0
9
9
42
17
0
0
0
0
0
0
0
9
% E
% Phe:
9
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
9
0
0
0
17
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
34
42
9
25
9
0
0
9
9
42
0
0
25
25
9
% K
% Leu:
0
0
0
0
0
9
42
0
25
9
0
9
0
0
25
% L
% Met:
0
0
0
0
0
17
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
34
0
0
9
42
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
50
0
% P
% Gln:
0
17
0
0
0
0
0
25
0
9
0
0
0
9
0
% Q
% Arg:
0
25
0
0
9
0
0
9
9
0
25
0
0
0
0
% R
% Ser:
42
0
0
9
0
9
9
0
9
0
9
59
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
75
0
9
34
0
9
9
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _